Mules are the logistics network of financial crime. Yet, until recently, they have managed to avoid much in the way of deliberate efforts by the state or by industry to deter, prevent, detect, or sanction their activities. But times, and, potentially, the business case for investing in proactive mule detection solutions… they are a-changin’. This panel will discuss how and why the business case for proactive mule detection is changing, some examples of how such solutions work and their benefits, and some examples of leading practices and unexpected benefits that have stemmed from them.